單位
生物資源學系,分子生物科技學系
職稱
教授
最高學歷
台灣大學畜產學研究所博士
分機
4253
電子郵件
bellchen@mail.dyu.edu.tw
辦公室
J301-12
專長
n.a.
課表

經歷

教授

大葉大學

分子生物科技學系

2017-08-01~迄今

教授

大葉大學

生物資源學系

2010-02-01~迄今

主任

大葉大學

創新育成中心

2013-02-01~2013-08-31

研發長

大葉大學

研究發展處

2010-10-01~2013-09-30

主任

大葉大學

生物資源學系

2010-02-01~2011-07-31

副院長

大葉大學

生物科技暨資源學院院部

2010-02-01~2010-09-30

主任

大葉大學

分子生物科技學系

2006-08-01~2009-07-31

教授

大葉大學

分子生物科技學系

2015-08-01~2017-07-31

教授

大葉大學

分子生物科技學系

2014-08-01~2015-07-31

教授

大葉大學

分子生物科技學系

2010-02-01~2011-07-31

教授

大葉大學

分子生物科技學系

2009-02-01~2010-01-31

副教授

大葉大學

分子生物科技學系

2005-08-01~2009-01-31

助理教授

大葉大學

分子生物科技學系

2003-08-01~2005-07-31

助理教授

大葉大學

農業生物科技研究所

2002-02-07~2003-07-31

歷年授課

暫無資料

學術著作

期刊論文

Min-Yu Tu, Chen Hsiao Ling, Yu-Tang Tung, Chao-Chih Kao, Fu-Chang Hu and Chuan-Mu Chen,"Short-term effects of kefir-fermented milk consumption on bone mineral density and bone metabolism in a randomized clinical trial of osteoporotic patients.," PLOS ONE, Vol.10, No.12, United States Of America, Nov 2015, pp.eArticle-e0144231.

期刊論文

Yi-Ling Lin, Chen Hsiao Ling, Shao-Bin Cheng, Dah-Cherng Yeh, Chu-Chun Huang, Fang-Ku P’eng, Tung-Chou Tsai, Cheng-Chung Wu and Chuan-Mu Chen,"Methylation-silencing RCC1 expression is associated with tumorigenesis and depth of invasion in gastric cancer.," INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL PATHOLOGY, Vol.8, No.11, United States Of America, Nov 2015, pp.14257-14269.

期刊論文

C. W. Kuo, C. J. Shen, Yu-Tang Tung, Chen Hsiao Ling, Yu-Hsuan Chen, Wen-Hui Chang, Kai-Chung Cheng, Shang-Hsun Yang and Chuan-Mu Chen,"Extracellular superoxide dismutase ameliorates streptozotocin-induced diabetic nephropathy via inhibiting the ROS/ERK1/2 signaling.," LIFE SCIENCES, Vol.135, No.5, United Kingdom, Nov 2015, pp.77-86.

期刊論文

Tung-Chou Tsai, Yu-Tang Tung, Yueh-HsiungKuo, Jiunn-WangLiao, Hsin-Chung Tsai, Kowit-YuChong, Chen Hsiao Ling and Chuan-Mu Chen,"Anti-inflammatory effects of Antrodia camphorata, an herbal medicine, in a mouse skin ischemia model.," JOURNAL OF ETHNOPHARMACOLOGY, Vol.159, No.3, United Kingdom, Nov 2015, pp.113-121.

期刊論文

Chen Hsiao Ling, Yu-Tang Tung, Chia-Hui Chuang, Min-Yu Tu, Tung-Chou Tsai, Shou-Yi Chang and Chuan-Mu Chen,"Kefir improves bone mass and microarchitecture in an ovariectomized rat model of postmenopausal osteoporosis.," OSTEOPOROSIS INTERNATIONAL, Vol.26, No.2, United States Of America, Nov 2015, pp.589-599.

期刊論文

Zi-Lun Lai, Yung-An Tsou, Shin-Ru Fan, Ming-Hsui Tsai, Chen Hsiao Ling, Nai-Wen Chang, Ju-Chien Cheng and Chuan-Mu Chen,"Methylation-Associated Gene Silencing of RARB in Areca Carcinogens Induced Mouse Oral Squamous Cell Carcinoma," BIOMED RESEARCH INTERNATIONAL, United States Of America, Oct 2014, pp.1-14.

期刊論文

Chih-Jie Shen, Yung-An Tsou, Chen Hsiao Ling, Hung-Jin Huang, Shinn-Chih Wu, Winston T. K. Cheng, Calvin Yu-Chian Chen and Chuan-Mu Chen,"Osteoponin Promoter Controlled by DNA Methylation:Aberrant Methylation in Cloned Porcine Genome," BIOMED RESEARCH INTERNATIONAL, Vol.2014, No.e327538, United States Of America, Oct 2014.

期刊論文

Chen Hsiao Ling, Chih-Ching Yen, Shih-Ming Wang, Tung-Chou Tsai, Zi-Lun Lai, Jheng-Yue Sun, Willei Lin, Wu-Huei Hsu and Chuan-Mu Chen,"Aerosolized bovine lactoferrin reduces lung injury and fibrosis in mice exposed to hyperoxia," BIOMETALS, Vol.27, Netherlands, Oct 2014, pp.1057-1068.

期刊論文

Cheng-Wei Lai, Chen Hsiao Ling, Ken-Yo Lin, Fang-Chueh Liu, Kowit-Yu Chong, Winston T. K. Cheng and Chuan-Mu Chen,"FTSJ2, a Heat Shock-Inducible Mitochondrial Protein, Suppresses Cell Invasion and Migration," PLOS ONE, Vol.9, No.e90818, United States Of America, Oct 2014.

期刊論文

Yu-Tang Tung, Ting-Yu Tang, Chen Hsiao Ling, Shang-Hsun Yang, Kowit-Yu Chong, Winston T. K. Cheng and Chuan-0u Chen,"Lactoferrin protects against chemical-induced rat liver fibrosis by inhibiting stellate cell activation," JOURNAL OF DAIRY SCIENCE, Vol.97, No.6, United States Of America, Oct 2014, pp.3281-3291.

期刊論文

Chen Hsiao Ling, Y-T Tung, C-L Tsai, C-W Lai, Z-L Lai, H-C Tsai, Y-L Lin, C-H Wang and C-M Chen,"Kefir improves fatty liver syndrome by inhibiting the lipogenesis pathway in leptin-deficient ob/ob knockout mice," INTERNATIONAL JOURNAL OF OBESITY, Vol.38, No.9, United Kingdom, Oct 2014, pp.1172-1179.

期刊論文

Yu-Tang Tung, Tung-Chou Tsai, Yueh-Hsiung Kuo, Chih-Ching Yen, Jheng-Yue Sun, Wen-Hui Chang, Chen Hsiao Ling and Chuan-Mu Chen,"Comparison of solid-state-cultured and wood-cultured Antrodia camphorata in anti-inflammatory effects using NF-κB/luciferase inducible transgenic mice.," PHYTOMEDICINE, Vol.21, No.2014, United States Of America, Oct 2014, pp.1708-1716.

期刊論文

Hsu-Chung Liu, Shun-Yuan Pai, Chen Hsiao Ling, Cheng-Wei Lai, Tung-Chou Tsai, Winston T. K. Cheng, Shang-Hsun Yang and Chuan-Mu Chen,"Recombinant Derp5 secreted in the milk leading by aS1-casein signal peptide protects against dust mite allergen-induced airway inflammation.," JOURNAL OF DAIRY SCIENCE, Vol.97, No.9, United States Of America, Oct 2014, pp.6792-6803.

會議論文

Chuan-Mu Chen, Zi-Lun Lai, Chih-Ching Yen, Miao-Ling Wang and Chen Hsiao Ling,"Cloning and Expression of the Human Extracellular Superoxide Dismutase (EC-SOD) Gene in Probiotic Lactobacillus casei," 2013 3rd International Conference on Environmental, Biomedical and Biotechnology ICEBB, 新加坡, Singapore, Sep 2013

期刊論文

Chuan-Mu Chen, Zi-Lun Lai, Chih-Ching Yen, Miao-Ling Wang and Chen Hsiao Ling,"Cloning and expression of human extracellular superoxide dismutase (EC-SOD) gene in probiotic Lactobacillus casei," Int. J. Biosci. Biochem. Bioinform, Vol.3, No.6, United States Of America, Sep 2013, pp.557-561.

期刊論文

Chen Hsiao Ling, Tung-Chou Tsai, Jan-Chi Huang, De-Chi Wang and Chuan-Mu Chen,"Dimorphic goat amelogenin alleles on sex chromosomes for gender determination of preimplantation embryos," International Journal of Bioscience, Biochemistry and Bioinformatics, Vol.3, No.6, United States Of America, Sep 2013, pp.619-623.

期刊論文

Sen-Wei Tsai, Chen Hsiao Ling, Yi-Chun Chang and Chuan-Mu Chen,"Molecular Mechanisms of Treadmill Therapy on Neuromuscular Atrophy Induced via Botulinum Toxin A," NEURAL PLASTICITY, Vol.2013, No.2013, United States Of America, Sep 2013, pp.59327-59327.

期刊論文

Chih-Jie Shen, Chiao-Chieh Lin, Perng-Chih Shen, Winston T.K. Cheng, Chen Hsiao Ling, Tsung-Chou Chang, Shyh-Shyan Liu and Chuan-Mu Chen,"Imprinted Genes and Satellite Loci Are Differentially Methylated in Bovine Somatic Cell Nuclear Transfer Clones," CELLULAR REPROGRAMMING, Vol.15, No.5, United States Of America, Sep 2013, pp.413-424.

期刊論文

Chen Hsiao Ling, Shih-Tao Wen, Wei Chen, Cheng-Wei Lai, Chih-Ching Yen, Kun-Hsiung Lee, Shinn-Chih Wu and Chuan-Mu Chen,"Amniotic Fluid Stem Cells from EGFP Transgenic Mice Attenuate Hyperoxia-Induced Acute Lung Injury," PLOS ONE, Vol.8, No.9, United States Of America, Sep 2013, pp.1-12.

會議論文

Chen Hsiao Ling,"Identification and Characterization of Novel Antihypertensive Peptides Obtained from Fermented Milk," The 13th International Conference on Endothelin, 東京, Japan, Sep 2013

期刊論文

Chen, Wei, Chen, Jiun-Yu, Tung, Yu-Tang, Chen Hsiao Ling, Kuo, Chia-Wen, Chuang, Chia-Hui, Chong, Kowit-Yu, Mao, Frank Chiahung, Chen and Chuan-Mu,"High-Frequency Ultrasound Imaging to Evaluate Liver Fibrosis Progression in Rats and Yi Guan Jian Herbal Therapeutic Effects," EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE, Vol.2013, No.Article ID, United States Of America, Sep 2013, pp.1-12.

期刊論文

Yu-Tang Tung, Chen Hsiao Ling, Hsing-Chung Tsai, Shang-Hsun Yang, Yi-Chun Chang and Chuan-Mu Chen,"Therapeutic Potential of Andrographolide Isolated from the Leaves of Andrographis paniculata Nees for Treating Lung Adenocarcinomas," EVIDENCEBASED COMPLEMENTARY AND ALTERNATIVE MEDICINE, Vol.2013, No.305898, United States Of America, Sep 2013, pp.1-9.

期刊論文

Chen Hsiao Ling, Hsu-Chung Liu, Shun-Yuan Pai, Winston TK Cheng, Tung-Chou Tsai, Shang-Hsun Yang and Chuan-Mu Chen,"Ingestion of milk containing the Dp2 peptide, a dust mite allergen, protects mice from allergic airway inflammation and hyper-responsiveness.," ALLERGY ASTHMA AND CLINICAL IMMUNOLOGY, Vol.9, No.1, Republic of Korea, Sep 2013, pp.1-11.

期刊論文

Yu-Tang Tung, Chen Hsiao Ling, Cheng-Yu Lee, Yu-Ching Chou, Po-Ying Lee,, Hsin-Chung Tsai, Yi-Ling Lin and Chuan-Mu Chen,"Active Component of Danshen (Salvia miltiorrhiza Bunge),," EVIDENCEBASED COMPLEMENTARY AND ALTERNATIVE MEDICINE, Vol.2013, No.319247, United States Of America, Sep 2013.

期刊論文

Chen Hsiao Ling, Yu-Tang Tung, Chih-Ching Yen, Po-Ying Lee, Hsin-Chung Tsai, Ming-Fong Lin and Chuan-Mu Chen,"Bovine lactoferrin inhibits lung cancer growth through suppression of both inflammation and expression of vascular endothelial growth factor," JOURNAL OF DAIRY SCIENCE, Vol.96, No.4, United States Of America, Sep 2013, pp.2095-2106.

會議論文

Chen Hsiao Ling, Yu-Tang Tung, Cheng-Yu Lee, Yu-Ching Chou, Po-Ying Lee, Hsin-Chung Tsai and Chuan-Mu Chen,"Tanshinone I attenuates lung tumorigenesis via inhibitions of VEGF, Cyclin A and Cyclin B expression," The Proceeding of the 5th International Conference on Drug Discovery and Therapy, 杜拜, United Arab Emirates, Sep 2013

會議論文

Yu-Tang Tung, Chen Hsiao Ling, Hsin-Chung Tsai, Shang-Hsun Yang, Yi-Chun Chang and Chuan-Mu Chen,"Therapeutic potential of andrographolide isolated from the leaves of Andrographis paniculata Nees for treating lung adenocarcinomas," The Proceeding of the 5th International Conference on Drug Discovery and, 杜拜, United Arab Emirates, Sep 2013

會議論文

林雯婷, 黃端文, 陳小玲, 施英隆, 吳建一,"利用固定化 Klebsiella sp. Wul 菌株提高生產2,3-丁二醇之可行性研究," 2013第三屆綠色永續生物技術研討會, 大葉大學, 中華民國, 2013年2月

期刊論文

Chen Hsiao Ling, Sen-Wei Tsai,, Yu-Tang Tung, Chih-Jie Shen, Chia-Hui Chuang,, Ting-Yu Tang and Chuan-Mu Chen,"Treadmill running upregulates the expression of acetylcholine receptor in rat gastrocnemius following botulinum toxin A injection.," JOURNAL OF ORTHOPAEDIC RESEARCH, Vol.31, No.1, United States Of America, Sep 2013, pp.125-131.

會議論文

G. J. Wang, Chen Hsiao Ling and C. M. Chen,"Production of recombinant casein phosphopeptide trimer using Pichia pastoris," In the 2012 Conference of Taiwan Society for Biochemistry and Molecular Biology, 南投, R.O.C, Aug 2012

會議論文

W.H. Chang, Chen Hsiao Ling, C. C. Yen and C.M. Chen,"Anti-inflammatory pathway of lactoferrin on hyperoxia-induced lung inflammatory responses using NF-κB/luciferase transgenic mice," In the 2012 Eleventh Annual AACR International Conference on Frontiers in Cancer Prevention Research, 阿納海姆, United States Of America, Aug 2012

會議論文

Y. T. Tung, Chen Hsiao Ling and C. M. Chen,"Tanshinone I attenuates lung tumorigenesis in VEGF-overexpressing transgenicmice via inhibition of tumor-activated cell cycle pathway," In the 2012 Eleventh Annual AACR International Conference on Frontiers in Cancer Prevention Research, 阿納海姆, United States Of America, Aug 2012

會議論文

Y. T. Tung, Chen Hsiao Ling, H. C. Tsai, S. H. Yang, Y. C. Chang and C. M. Chen,"Therapeutic potential of andrographolide for treating lung adenocarcinomas," In the 5th International Conference on Industrial Bioprocesses, 台北, R.O.C, Aug 2012

會議論文

C. J. Shen, W. T. K. Cheng, J. Y. Cheng, Chen Hsiao Ling and C. M. Chen,"Production of multimeric methyl-binding domain (MBD) protein for genome- wide hypermethylated genes screening," In the 5th International Conference on Industrial Bioprocesses, 台北, R.O.C, Aug 2012

會議論文

C. M. Chen, Y. T. Tung, Y. W. Lai, M. L. Wang, T. C. Tsai and Chen Hsiao Ling,"Cloning and expression of human extracellular superoxide dismutase gene (EcSOD) in food-grade Lactobacillus casei," In the 5th International Conference on Industrial Bioprocesses, 台北, R.O.C, Aug 2012

會議論文

W.H. Chang, Chen Hsiao Ling and C.M. Chen,"Anti-inflammatory effect of lactoferrin on hyperoxia-induced systemic inflammatory responses using NF-κB/luciferase transgenic mice.," In the 2012 Asia-Pacific Development Biology Conference., 台北, R.O.C, Aug 2012

會議論文

C.W. Lai, Chen Hsiao Ling and C.M. Chen,"The position effect of transgenic mice causes EGFP gender differential expression in liver," In the 2012 Asia-Pacific Development Biology Conference, 台北, R.O.C, Aug 2012

會議論文

Lu-Tzu Chen, Chen Hsiao Ling and C.M. Chen,"Nuclear factor kappa B plays an important role during the spermatogenesis development of testis," In the 2012 Asia-Pacific Development Biology Conference, 台北, R.O.C, Aug 2012

期刊論文

Chen, JY, Chen Hsiao Ling, J. C. Cheng, H. J. Lin, Y. T. Tung, C. F. Lin and C.M. Chen,"A Chinese herbal medicine, Gexia-Zhuyu Tang (GZT), prevents dimethylnitrosamine-induced liver fibrosis through inhibition of hepatic stellate cells proliferation," JOURNAL OF ETHNOPHARMACOLOGY, Vol.142, No.3, Ireland, Aug 2012, pp.811-818.

會議論文

Chen Hsiao Ling, Y. W. Lai and C. M. Chen,"Epigenetic silence of DnaJD1 gene in hepatitis B virus X protein–positive hepatocellular carcinoma," In The 2012 FASEB Summer Research Conference on “Liver Biology: Fundamental Mechanisms & Translational Applications, 斯諾馬斯村, United States Of America, Aug 2012

會議論文

Chen Hsiao Ling, C. Y. Chen and C. M. Chen,"A Chinese herbal medicine, Gexia-Zhuyu Tang (GZT), prevents dimethylnitrosamine-induced liver fibrosis through inhibition of hepatic stellate cells proliferation.," In The 2012 FASEB Summer Research Conference on “Liver Biology: Fundamental Mechanisms & Translational Applications., 斯諾馬斯村, United States Of America, Aug 2012

會議論文

C. M. Chen, H. C. Liu, S. Y. Pai, W. T. K. Cheng and Chen Hsiao Ling,"Oral administration of transgenic Dp2 peptide-enriched milk induces tolerance from allergic asthma," In The 2012 Experimental Biology International Meeting: Translating Science for Tomorrow’s Health., 聖地牙哥, United States Of America, Aug 2012

期刊論文

S. W. Tsai, C. J. Chen, Chen Hsiao Ling, C. M. Chen and Y. Y. Chang,"The effects of treadmill running on rat gastrocnemius function following botulinum toxin A injection," JOURNAL OF ORTHOPAEDIC RESEARCH, Vol.30, No.2, United States Of America, Aug 2012.

期刊論文

C. J. Shen, W. T. K. Cheng, S. C. Wu, Chen Hsiao Ling, T. C. Tsai, S. H. Yang and C.M. Chen,"Differential differences in methylation status of putative imprinted genes among cloned swine genomes," PLOS ONE, Vol.7, No.2, United States Of America, Aug 2012.

期刊論文

J. Y. Chen, Chen Hsiao Ling, S. H. Wu, T. C. Tsai, C. C. Yen, W. H. Hsu, W. Chen and C. M. Chen,"Application of high-frequency ultrasound for the detection of surgical anatomy in the rodent abdomen," VETERINARY JOURNAL, Vol.191, No.2, United Kingdom, Aug 2012, pp.246-252.

會議論文

Chen Hsiao Ling and Chuan-Mu Chen,"Curcumin reduces pulmonary tumorigenesis in human vascular endothelial growth factor A165 (hVEGF A165)-overexpressing transgenic mice," proceeding of 19th Annual International Conference on ISCB, 奧地利, United Kingdom, Jul 2011

會議論文

Chuan-Mu Chen and Chen Hsiao Ling,"Granzyme G, a serine protease, is expressed in the two-cell stage mouse embryo and is required for the maternal-zygotic transition.," 19th Annual International Conference on ISCB, 奧地利, United Kingdom, Jul 2011

期刊論文

Y. T. Chang, C. M. Chen, M. Y. Tu, Chen Hsiao Ling, S. Y. Chang, T. C. Tsai, Y. T. Wang and H. L. Hsiao,"Effects of osteoporosis and nutrition supplements on structures and nanomechanical properties of bone tissue. J. Mechan. Behav. Biomed. Materi.," JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS, Vol.4, United Kingdom, Jul 2011, pp.1412-1420.

期刊論文

Che-Ming Hung, Chia-Chou Yeh, Kowit-Yu Chong, Chen Hsiao Ling, Jiun-Yu Chen, Shung-Te Kao, Chih-Ching Yen, Ming-Hsien Yeh, Maw-Sun Lin and Chuan-Mu Chen,"Gingyo-San Enhances Immunity and Potentiates Infectious Bursal Disease Vaccination," EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE, United Kingdom, Jul 2011, pp.1-10.

期刊論文

T. C. Tsai, S. H. Wu, Chen Hsiao Ling, Y. T. Tung, W. T. K. Cheng, J. C. Huang and C. M. Chen,"Identification of sex-specific polymorphic sequences in goat amelogenin gene for embryo sexing.," JOURNAL OF ANIMAL SCIENCE, Vol.89, United Kingdom, Jul 2011, pp.2407-2414.

期刊論文

Y. T. Tung, Chen Hsiao Ling, C. W. Lai, C. J. Shen, Y. W. Lai and C. M. Chen,"Curcumin reduces pulmonary tumorigenesis in vascular endothelial growth factor (VEGF)-overexpressing transgenic mice.," MOLECULAR NUTRITION & FOOD RESEARCH, Vol.55, United Kingdom, Jul 2011, pp.1036-1043.

期刊論文

Chen Hsiao Ling, H. J. Lin, J. Y. Chen, C. F. Lin, S. T. Kao, J. C. Cheng and C.M. Chen,"Hepatoprotective effects of Yi Guan Jian, an herbal medicine, in rats with dimethylnitrosamine- induced liver fibrosis," JOURNAL OF ETHNOPHARMACOLOGY, Vol.134, United Kingdom, Jul 2011, pp.953-960.

期刊論文

C. C. Yen, C. J. Shen, W. H. Hsu, Y. H. Chang, H. T. Lin, Chen Hsiao Ling and C. M. Chen,"Lactoferrin – an iron-binding antimicrobial protein against Escherichia coli infection," BIOMETALS, Vol.24, United Kingdom, Jul 2011, pp.585-594.

期刊論文

C. M. Hung, S. C. Wu, C. C. Yen, M. F. Lin, Y. W. Lai, Y. T. Tung, Chen Hsiao Ling and C. M. Chen,"Porcine lactoferrin as feedstuff additive elevates avian immunity and potentiates vaccination.," BIOMATERIALS, Vol.23, United Kingdom, Jun 2010, pp.579-587.

期刊論文

F. C. Liu, Chen Hsiao Ling, W. Lin, Y.T. Tang, C.W. Lai, A. L. Hsu and C. M. Chen,"Application of porcine lipase secreted by Pichia pastoris to improve fat digestion and growth performance of postweaning piglets.," JOURNALOFAGRICULTURALANDFOODCHEMISTRY, Vol.58, United Kingdom, Jun 2010, pp.3322-3329.

期刊論文

Chen Hsiao Ling, Y.W. Lai, C. S. Chen, T. W. Chu, W. Lin, C. C. Yen, M. F. Lin, M.Y. Tu and C. M. Chen,"Probiotic Lactobacillus casei expressing human lactoferrin elevates antibacterial activity in the gastrointestinal tract.," BIOMATERIALS, Vol.23, United Kingdom, Jun 2010, pp.543-554.

期刊論文

Chen Hsiao Ling, C. M. Hung, C. C. Yeh, C.W. Lai, M.F. Kuo, M. H. Yeh, W. Lin,, M.Y. Tu, H. C. Cheng and C. M. Chen,"Porcine lactoferrin administration enhances peripheral lymphocyte proliferation and assists infectious bursal disease vaccination in native chickens.," VACCINE, Vol.28, United Kingdom, Jun 2010, pp.2895-2902.

會議論文

C. M. Chen, C. C. Yen and Chen Hsiao Ling,"Lactoferrin as a natural regimen of selective decontamination of the digestive tract.," IXth International Conference on Lactoferrin, Beijing, China., United Kingdom, May 2009

會議論文

Chen Hsiao Ling, C. C. Yen, T. C. Tsai and C. M. Chen,"Recombinant porcine lactoferrin expressed in the milk of transgenic mice enhances offspring growth performance.," IXth International Conference on Lactoferrin., Beijing, China., United Kingdom, May 2009

期刊論文

Chih-Ching Yen, Chien-Yu Lin, Kowit-Yu Chong, Tung-Chou Tsai, Chih-Jie Shen, Ming-Fong Lin, Chun-Yao Su, Chen Hsiao Ling and Chuan-Mu Chen1,"Lactoferrin as a natural regimen of selective decontamination of the digestive tract: Recombinant porcine lactoferrin expressed in the milk of transgenic mice protects neonates from pathogen challenges in the gastrointestinal tract.," JOURNAL OF INFECTIOUS DISEASES, Vol.199, United Kingdom, May 2009, pp.590-598.

期刊論文

Liu, F.C, Chen Hsiao Ling, K. Y. Chon, A. L. Hsu and C. M. Chen.,"Production of recombinant porcine colipase secreted by Pichia pastoris and its application to improve dietary fat digestion and growth of postweaning piglets.," BIOTECHNOLOGY PROGRESS, Vol.24, No.6, United Kingdom, Apr 2008, pp.1333-1341.

會議論文

C. M. Chen,, Chen Hsiao Ling, C. M. Hung and W.T.K. Cheng,"Lactoferrin-enriched milk protects neonatal from a lethal challenge with enterovirus type 71.," In International Conference of 2008 Nutrigenomics, Paris, France., United Kingdom, Apr 2008

期刊論文

Chen Hsiao Ling, J. Y. Huang, T. W. Chu, T. C. Tsai, C. M. Hung, C. C. Lin, F. C. Liu, L. C. Wang, Y. J. Chen, M. F. Lin and C. M. Chen,"Expression of VP1 protein in the milk of transgenic mice: As a potential oral vaccine against for enterovirus 71 strain infection," VACCINE, Vol.26, United Kingdom, Apr 2008, pp.2882-2889.

會議論文

Chen Hsiao Ling, C. C. Yen and C. M. Chen,"Lactoferrin-enriched milk reduces need for antibiotics in animal feed and enhances offspring growth performance.," International Conference of 2008 Nutrigenomics, Paris, France., United Kingdom, Apr 2008

期刊論文

Chen Hsiao Ling, L. C. Wang,, C. H. Chang, C. C. Yen, W.T.K. Cheng, S. C. Wu, C. M. Hung, M. F. Kuo and C. M. Chen,"Recombinant Porcine Lactoferrin Expressed in the Milk of Transgenic Mice Protects Neonatal Mice from a Lethal Challenge with Enterovirus Type 71," VACCINE, Vol.26, United Kingdom, Apr 2008, pp.891-898.

期刊論文

Chen Hsiao Ling, S. C. Wu, C. C. Yen, M. F. Kuo, T. S. Yang, S. R. Wang,, C. N. Weng, C. M. Chen, and W. T. K. Chen,"Recombinant porcine lactoferrin expressed in the milk of transgenic mice enhances offspring growth performance," JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, Vol.55, United Kingdom, Mar 2007, pp.4670-4677.

會議論文

Chen, C. M, C. C. Yen and H. L. Chen,"Synthetic porcine lactoferricin with 20-residue peptide exhibits antimicrobial activity against Escherichia coli, Staphylococcus aureus and Candida albicans.," International Symposium on “Functional Foods in Europe – International Developments in Science and Health Claims” , 9-11 May, Malta., United Kingdom, Mar 2007

期刊論文

Chen, H. L., C. C. Yen, T. C. Tsai, C. H. Yu, Y. J. Liou, Y. W. Lai, M. L. Wang and C. M. Chen,"Production and characterization of human extracellular superoxide dismutase (ECSOD) in the methylotrophic yeast Pichia pastoris.," JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, Vol.54, No.21, United Kingdom, Feb 2006, pp.8041-8047.

會議論文

Chen, C. M., Chen, W. E., Wu, J. C., Chen and H. L.,"Epigenetic down-regulation of death-associated protein kinase in hepatocellular carcinama," 12 th International Symposium on Viral Hepatitis and Liver Disease, United Kingdom, Feb 2006

期刊論文

Hsiao-Ling Chen, C. C. Yen, C. Y. Lu, C. H. Yu and C. M. Chen,"Synthetic porcine lactoferricin with a 20-residue peptide exhibits antimicrobial activity against Escherichia coli, Staphylococcus aureus, and Candida albicans," Journal of Agricultural and Food Chemistry, Vol.54, No.9, United Kingdom, Feb 2006, pp.3277-3282.

會議論文

G. J. Huang, S. T. Chen, K. T. Yeh and C. M. Chen,"3OST3B promoter aberrant methylation and its clinicopathological features in Taiwan breast cancer tissues.," In Proc. of the 21th Joint Annual Conference of Biomedical Sciences. P505. NDU, Taipei, Taiwan., United Kingdom, Feb 2006, pp.505-505

期刊論文

J. R. Liu, S. Y. Wang, M. J. Chen, Hsiao-Ling Chen, P.Y Yueh and C.W Lin,"Hypocholesterolaemic effects of milk-kefir and soymilk-kefir in cholesterol-fed hamsters," BRITISH JOURNAL OF NUTRITION, Vol.95, United Kingdom, Feb 2006, pp.939-946.

期刊論文

Lai, Y. W., Yen, C. C., Lin,Y. Y., Lu, C. Y., Yang, S. H., Tsai, T. C., Lin, Y. J., Chen, C. M. and Chen Hsiao Ling,"Production of recombinant porcine lactoferrin exhibiting antibacterial activity in methylotrophic yeast, Pichia pastoris," Journal of Molecular Microbiology and Biotechnology, Vol.8, No.3, United Kingdom, Jan 2005.

會議論文

Gwo-Jen Huang, Shou-Tung Chen and Chuan-Mu Chen,"Promoter hypermethylation and aberrant mRNA expression of heparan sulfate D-glucosaminyl 3-O-sulfotransferase(3OST3B) gene in Taiwan breast cancer tissue.," "Proc. of the 13th Symp. on Recent Advanes in Cellular and Molecular Biology", Ping Tung, Taiwan, United Kingdom, Jan 2005, pp.55-55

會議論文

王妙鈴, 陳全木, 蔡東州,"人類胞外超氧歧化脢於乳酸桿菌中之表現與抗氧化活性分析," 中國畜牧學會會誌, United Kingdom, 2004年12月, pp.289-289

會議論文

Lai, Y. W., Yang, S. H., Lin, C. W., Chen and C. M.,"Production of recombinant porcine lectoferrrin with bactericidal activity in Pichia pastoris.," " Symp . 11th AAAP Congress", Kuala Lumpur, Malaysia., United Kingdom, Dec 2004, pp.260-262

會議論文

Chen, Y. P., Chen, C. M., Lin and C.W.,"Angiotensin converting enzyme inhibitory activity of kefir.," "Symp . 11th AAAP Congress", Kuala Lumpur, Malaysia., United Kingdom, Dec 2004, pp.280-282

會議論文

Wang, M. L., Chen, C. W., Tsai and T. C.,"Cloning and expression of human extracellular superoxide dismutase gene in Lactobacillus casei.," "Proc. of the 19th Joint Annual Conference of Biomedical Science", Taipei, Taiwan., United Kingdom, Dec 2004, pp.207-207

會議論文

Chen, C. M., Huang and T. H.-M,"Loss of expression and aberrant promoter methylation of the PCDH21(protocadherin) gene in breast tumors.," " Proc. of AACR Special Conference of Advances in Breast Cancer Research: Genetics, Biology and Clinical Applications", Huntington Beach, California, USA., United Kingdom, Nov 2003

期刊論文

Chen, C. M., Hsiau, T. H. -C., Hsiau, A. H. -A., Shi, H., Brock, G.J.R., Caldwell, C.W., Yan, P. S., Huang, T. H. -M. and Chen Hsiao Ling,"Methylation target array for rapid analysis of CpG island hypermethylation in multiple tissue genomes.," Am. J. Pathol., Vol.163, No.1, United Kingdom, Nov 2003.

會議論文

Tai, T. C., Chen and C. M.,"A novel methylation CpG island microarray-based screening of the potential human imprinting genes," "Proc. of the 18th Joint Annual Conference of Biomedical Science", Taipei, Taiwan., United Kingdom, Nov 2003, pp.68-68

會議論文

Yan, P. S., Weinmann, A., Shi, H., Wei, S. H., Rodriguez, F. J., Raosthmatpanah, F., Farnham, P., Huang and T. H.-M.,"Identification of E2F target promoters frequently hypermethylated in solid tumors.," “Proc. of the 93th Annual Meeting of the American Association for Cancer Research”, p.160, San Francisco, California, USA., United Kingdom, Oct 2002

期刊論文

Yan,P. S., Efferth, T., Lin, J., Rodel, L., Fuzesi, L., Huang and T. H.-M.,"Use of CpG island microarrays to identify colorectal tumors with a high degree of concurrent methylation," Methods, Vol.27, United Kingdom, Oct 2002.

會議論文

Lin, C.W., Lu, C.Y., Chen and C.M.,"Development of probiotic transformant carrying human lactoferrin gene.," Xth International Congress. New Delhi, India. Asian-Australasian Association of Animal Production Societies., United Kingdom, Oct 2002, pp.219-219

會議論文

Chen, C. M., Huang and T. H.-M,"Methylation tissue array : a novel technique for simultaneous analysis of extensive DNA hypermethylation in multiple breast tumors," "Proc. of the 93th Annual Meeting American Association for Cancer Research" San Francisco, California, USA., United Kingdom, Oct 2002

期刊論文

Lin, C. W., Yan, J. H., Su, H. P., Huang and C. C.,"Studies on the processing property an interaction between porcine blood proteins and waxy rice starch during making porcine blood cake," Asian-Aus. J. Anim. Sci, Vol.14, No.3, United Kingdom, Sep 2001.

期刊論文

Chen, C. M., Cheng, W. T. K., Chang, Y. C., Chang and T. J.,"Growth enhancement of simulated country chickens by dietary administration of recombinant yeast cultures containing enriched growth hormone," Life Sci, Vol.67, No.17, United Kingdom, Aug 2000, pp.2103-2115.

期刊論文

陳明汝, 王聖耀, 林慶文,"利用根黴菌株凝乳酵素試製扣碗酪," 中華農學會報, Vol.1, United Kingdom, 2000年, pp.131-141.

期刊論文

Chen, C. M., Chang, Y. C., Cheng and W. T. K.,"High-level expression of growth hormone in the methylotropic yeast and its application on growth improvement of fowls.," Asian-Aus. J. Anim. Sci., Vol.13, No.Supl., United Kingdom, Aug 2000.

期刊論文

Lin, C. W., Liu and J. R.,"Identification and characterization of lactic acid bacteria and yeasts isolated from kefir grains in Taiwan.," Australia Journal Dairy Technology, Vol.54, No.1, United Kingdom, Jul 1999.

專案計畫

中國化學製藥股份有限公司

用以治療血管損傷或病變相關疾病之組合物(乳發酵產物之用途)

2018/11/01 ~ 1999/12/31

不認列

中國化學製藥股份有限公司

專利讓售-新穎抗高血壓月太及其用途

2018/08/13 ~ 9999/12/31

不認列

科技部 ( 一般 )

克弗爾於心血管疾病之預防與改善功效機制探討及其關鍵活性成分解析

2018/08/01 ~ 2019/07/31

已認列

科技部 ( 一般 )

克弗爾於心血管疾病之預防與改善功效機制探討及其關鍵活性成分解析

2017/08/01 ~ 2018/07/31

已認列

科技部 ( 一般 )

克弗爾發酵乳於自由基失衡衍生疾病之保健應用研究(3/3)

2016/08/01 ~ 2017/10/30

已認列

科技部 ( 一般 )

克弗爾發酵乳於自由基失衡衍生疾病之保健應用研究(2/3)

2015/08/01 ~ 2016/07/31

已認列

科技部 ( 一般 )

克弗爾發酵乳於自由基失衡衍生疾病之保健應用研究(1/3)

2014/08/01 ~ 2015/07/31

已認列

豐展生物科技股份有限公司

提升發酵菌株標的蛋白產製效率及其品質監控方法之建立

2014/01/01 ~ 2015/01/31

n.a.

102學年度第一學期補助大學校院學生出國參加國際性技藝能競賽及發明案

2013/08/06 ~ 2013/12/31

n.a.

科技部(一般)

102年度大專校院獎勵特殊優秀人才

2013/08/01 ~ 2014/07/31

n.a.

科技部 ( 一般 )

克弗爾發酵乳改善脂肪肝之保健功能開發與作用機制研究(2/2)

2013/08/01 ~ 2014/07/31

n.a.

經濟部中小企業處

102年度中小企業創新育成中心計畫

2013/01/01 ~ 2013/12/30

n.a.

豐展生物科技股份有限公司

細胞生長分化因子產程管控與品質檢測方法之建立

2013/01/01 ~ 2013/12/31

n.a.

教育部

101年度教育部私立大學校院發展計畫之要點獎勵

2012/12/10 ~ 2012/12/31

n.a.

教育部

101鼓勵學生參加藝術與設計類國際競賽計畫

2012/11/06 ~ 2013/01/31

n.a.

教育部

101年度大學校院創新創業紮根計畫

2012/08/01 ~ 2013/07/31

n.a.

科技部(一般)

101年度補助大專校院獎勵特殊優秀人才措施

2012/08/01 ~ 2013/07/31

n.a.

科技部 ( 一般 )

克弗爾發酵乳改善脂肪肝之保健功能開發與作用機制研究(1/2)

2012/08/01 ~ 2014/07/31

n.a.

科技部 ( 一般 )

新穎抗高血壓胜肱產製平台與安全性評估系統之建置(3/3)

2012/08/01 ~ 2013/07/31

n.a.

教育部

101年度獎勵私立大學校院校務發展計畫要點之獎勵經費

2012/01/01 ~ 2012/12/31

n.a.

豐展生物科技股份有限公司

促進食慾機能性飼料添加物之開發

2012/01/01 ~ 2012/12/31

n.a.

教育部

教學卓越精進專業實務計畫

2012/01/01 ~ 2012/12/31

n.a.

科技部 ( 一般 )

(總計畫)新穎抗高血壓胜?產製平台與安全性評估系統之建置-新穎抗高血壓胜?產製平台與安全性評估系統之建置2/3

2011/08/01 ~ 2012/07/31

n.a.

科技部 ( 一般 )

克弗爾發酵乳改善脂肪肝之保健功能開發與作用機制研究

2011/08/01 ~ 2012/07/31

n.a.

科技部(一般)

獎勵特殊優秀人才獎勵金

2011/08/01 ~ 2012/07/31

n.a.

科技部(一般)

獎勵特殊優秀人才獎勵金

2011/03/01 ~ 2011/12/31

n.a.

豐展生物科技股份有限公司

免疫調節功能性飼料添加物之開發

2011/01/01 ~ 2011/12/31

n.a.

教育部

教學卓越精進專業實務計畫

2011/01/01 ~ 2011/12/31

n.a.

科技部 ( 一般 )

(總計畫)新穎抗高血壓胜?產製平台與安全性評估系統之建置-新穎抗高血壓胜?產製平台與安全性評估系統之建置1/3

2010/08/01 ~ 2011/07/31

n.a.

科技部 ( 一般 )

重組乳鐵蛋白素多元體之產製與其抗菌特性研究(3/3)

2010/08/01 ~ 2012/04/30

n.a.

豐展生物科技股份有限公司

育成─抗病毒蛋白質與胜太產程管控與品質檢測方法之建立

2010/01/01 ~ 2010/12/31

n.a.

科技部 ( 一般 )

人類超氧歧化?(human ECSOD)之產製開發及其於預防心血管疾病之應用研究

2009/08/01 ~ 2010/07/31

n.a.

科技部 ( 一般 )

重組乳鐵蛋白素多元體之產製與其抗菌特性研究(2/3)

2009/08/01 ~ 2010/07/31

n.a.

豐展生物科技股份有限公司

育成─ 機能性生太產程管控與品質檢測方法之建立

2009/01/01 ~ 2009/12/31

n.a.

中化健康生技股份有限公司

開發共生微生物發酵系統生產新式抗高血壓 月生 月太及其商品化應用

2008/10/26 ~ 2018/10/25

n.a.

中國化學製藥股份有限公司-101年衍生利益金

開發共生微生物發酵系統生產新式抗高血壓 月生 月太及其商品化應用

2008/10/26 ~ 2018/10/25

n.a.

科技部 ( 產學 )

國家型科技計畫(產學合作)-開發共生微生物發酵系統生產新式抗高血壓胜?及其商品化應用(II)

2008/08/01 ~ 2009/10/31

n.a.

科技部 ( 一般 )

重組乳鐵蛋白素多元體之產製與其抗菌特性研究(1/3)

2008/08/01 ~ 2009/07/31

n.a.

科技部 ( 產學 )

國家型科技計劃-新式抗高血壓月升研究與商品雛型

2007/08/01 ~ 2008/07/31

n.a.

中國化學製

新式抗高血壓月升研究與商品雛型技轉金(中國化學製藥)

2007/08/01 ~ 2008/07/31

n.a.

科技部 ( 一般 )

重組抗菌活性乳鐵蛋白素之產製與應用

2007/08/01 ~ 2008/07/31

n.a.

台灣孟德爾生物科技股份有限

育成─開發酪酸梭菌共生菌系統為動物飼料添加用生菌劑計劃

2007/01/01 ~ 2007/12/31

n.a.

科技部 ( 一般 )

利用基因工程技術於微生物系統產製抗高血壓?之開發(3/

2006/08/01 ~ 2007/07/31

n.a.

農委會

生物活性peptides發酵乳之開發及抗高血壓特性探討-2

2006/01/01 ~ 2006/12/31

n.a.

農委會

生物活性胜?發酵乳之開發及抗高血壓特性之探討

2006/01/01 ~ 2006/12/31

n.a.

台灣孟德爾股份有限公司

育成─開發酪酸梭菌為飼料添加用生菌劑

2006/01/01 ~ 2006/12/31

n.a.

科技部 ( 一般 )

利用基因工程技術於微生物系統產製抗高壓?之開發(2/3)

2005/08/01 ~ 2006/07/31

n.a.

乳鐵蛋白系列產品之成分與功能驗證

2005/01/01 ~ 2005/12/31

n.a.

農委會

生物活性peptides發酵乳之開發及抗高血壓特性探討

2005/01/01 ~ 2005/12/31

n.a.

科技部(一般)

利用基因工程技術於微生物系統產製抗高血壓

2004/08/01 ~ 2005/07/31

n.a.

學校經費

營養及功能性成分分析技術開發

2004/08/01 ~ 2005/07/31

n.a.

乳鐵蛋白系列產品研發及檢驗方法之建立

2004/01/01 ~ 2004/12/31

n.a.

農委會

克弗爾抗高血壓活性成分之研究

2004/01/01 ~ 2004/12/31

n.a.

科技部(一般)

應用基因工程技術培育含超氧歧化?之酵母菌轉型株(II)重組SOD3之純化及活性分析

2003/08/01 ~ 2004/07/31

n.a.

福記冷凍食品股份有限公司

皮蛋與滷蛋入味技術之開發

2003/03/01 ~ 2003/12/31

n.a.

產品檢驗方法及標準規格之建立

2003/01/01 ~ 2003/12/31

n.a.

科技部(一般)

應用基因工程技術培育含超氧歧化?之酵母菌轉型株

2002/08/01 ~ 2003/07/31

n.a.

大葉大學(指導學生專題)

??綎鏗埻轎砮?楊妏蚚?m譋楢昜鷂踚粥啞黺笥?綎鏗俶?漺倚騕蠕?虴

2015/07/01 ~ 2016/02/28

已認列

專利

中華民國

乳發酵產物之用途(用以治療血管損傷或病變相關疾病之組合物)

2016-01-21 ~ 2034-09-12

I517853

大葉大學

陳小玲

其他

新穎抗高血壓月太及其用途

2012-06-13 ~ 2028-09-17

2036922

大葉大學

陳小玲,陳全木

中國

新穎抗高血壓月太及其用途

2008-09-08 ~ 2028-09-07

1012938

大葉大學中興大學

陳小玲,陳全木

中華民國

新穎抗高血壓月太及其用途

2011-06-11 ~ 2027-09-20

I343260

大葉大學

陳小玲,陳全木

專業技術轉移

台灣/發明

用以治療血管損傷或病變相關疾病之組合物(乳發酵產物之用途)

中國化學製藥股份有限公司

2018/11/01~9999/12/31

讓售

限台灣生產

台灣/發明

新穎抗高血壓月太及其用途

中國化學製藥股份有限公司

2018/08/13~9999/12/31

讓售

台灣/發明

開發共生微生物發酵系統生產新式抗高血壓 月生 月太及其商品化應用

中國化學製藥股份有限公司-102~105年衍生利益金

2008/10/26~2018/10/25

非專屬授權

台灣/發明

開發共生微生物發酵系統生產新式抗高血壓 月生 月太及其商品化應用

中國化學製藥股份有限公司-101年衍生利益金

2008/10/26~2018/10/25

非專屬授權

限台灣生產

台灣/發明

開發共生微生物發酵系統生產新式抗高血壓 月生 月太及其商品化應用

中化健康生技股份有限公司-106年衍生利益金

2008/10/26~2018/10/25

非專屬授權

限台灣生產

台灣/發明

開發共生微生物發酵系統生產新式抗高血壓 月生 月太及其商品化應用

中國化學製藥股份有限公司

2008/10/26~2018/10/25

非專屬授權

限台灣生產

學術獲獎

101年國家發明創作獎

經濟部

2012/10/01

2012台北國際發明暨技術交易展

經濟部

2012/09/01

99年國家發明創作獎發明獎銀牌

經濟部

2010/09/01

作品發表

暫無資料

證照

暫無資料

榮譽事蹟

暫無資料

其它研究表現

暫無資料

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